Grapeseed Oil
INCI · Vitis Vinifera Seed Oil · also Grapeseed Oil, Vitis Vinifera Oil
How it works
Grapeseed oil is extracted from the seeds of Vitis vinifera grapes, often as a byproduct of winemaking, and is high in linoleic acid, a polyunsaturated fatty acid associated with barrier repair and a lighter, less greasy skin feel than oleic-acid-rich oils. It also contains proanthocyanidins and other polyphenols with documented antioxidant activity, which help protect skin lipids and collagen from oxidative damage caused by UV exposure and environmental stressors.
The evidence
Laboratory and some clinical studies support the antioxidant and anti-inflammatory activity of grape seed extract compounds, including proanthocyanidins linked to collagen protection and wound healing in animal models. Its high linoleic acid content is consistent with research showing linoleic-acid-rich oils support barrier function and may be better tolerated by acne-prone skin than oleic-acid-dominant oils. Direct large-scale human trials on topical grapeseed oil specifically remain limited, with much of the antioxidant research instead focused on grape seed extract taken orally or used in concentrated serum form.
Suitability
- Oily and combination skin: linoleic-acid-rich profile suits acne-prone skin better than heavier oils
- Sensitive skin: generally well tolerated with low reported irritation
- Dry skin: usable but may require layering with richer occlusives
- Often used in massage oils and lightweight serums for its thin texture
Concentration
Grapeseed oil is typically used undiluted as a facial oil or blended into serums and lotions at varying percentages, often as a lighter alternative to richer plant oils like shea butter or argan oil. There is no established maximum safe percentage for topical use, though its high polyunsaturated fat content makes it prone to oxidation once opened, requiring cool, dark storage away from direct sunlight.
Conflicts & combinations
- Pairs well with vitamin C and other antioxidants for compounded protection
- Layers effectively over humectants like glycerin or hyaluronic acid
- No known conflicts with acids, retinoids, or peptides
- Best stored away from heat and light to prevent rancidity-related irritation
- dryness
- anti aging
- Effective from
- —
- Max safe
- 100%
Is grapeseed oil good for acne-prone skin?
Its high linoleic acid content is generally considered more suitable for acne-prone skin than oleic-acid-rich oils, though it still has a moderate comedogenic rating.
Does grapeseed oil go rancid quickly?
Yes, its high polyunsaturated fat content makes it prone to oxidation, so it should be stored in a cool, dark place and used within a few months of opening.
Can grapeseed oil be used on oily skin?
Yes, its lightweight, fast-absorbing texture makes it a common choice for oily and combination skin.
Is grapeseed oil the same as grape seed extract?
No, grapeseed oil is the pressed fatty oil, while grape seed extract is a concentrated source of polyphenols like proanthocyanidins, often used in serums rather than as an oil.
Is grapeseed oil safe during pregnancy?
Yes, topical grapeseed oil is considered safe during pregnancy.
- PubMedPMID 11134301 ↗