active

Sulfur

INCI · Sulfur · also Sulphur, Colloidal Sulfur

EWG safety

How it works

Elemental sulfur has been used topically for over a century to manage acne and oily skin, making it one of the oldest continuously used dermatological actives. It exerts mild keratolytic action, helping shed dead skin cells that clog pores, while also possessing antibacterial properties against Cutibacterium acnes, the bacterium implicated in inflammatory acne lesions. Sulfur additionally reacts with amino acids and skin oils in a way that generates trace hydrogen sulfide and pentathionic acid at the skin surface, contributing to both its keratolytic effect and its distinctive mattifying, oil-reducing action.

The evidence

Sulfur-containing formulations, often combined with sodium sulfacetamide in prescription-strength products, have been studied for acne and rosacea-associated papules and pustules, with clinical use supporting measurable reductions in inflammatory lesion counts over several weeks of use. It is considered a well-established, if old-fashioned, acne treatment with a long safety record, though it is generally viewed as less potent than benzoyl peroxide or topical retinoids for moderate-to-severe acne and is more often used as an adjunct or spot treatment.

Suitability

  • Suitable for oily and acne-prone skin, including those seeking an alternative to benzoyl peroxide due to bleaching of fabrics or excessive irritation.
  • Can be drying, so those with dry or sensitive skin should use sparingly, in lower concentrations, or in spot-treatment form only.
  • Its characteristic sulfurous odor is a common cosmetic drawback, though modern formulations use fragrance and processing techniques to reduce the smell.

Concentration

  • Common formulations range from 2–10% sulfur.
  • Spot treatments and clay masks often sit at the higher end, while leave-on lotions and daily formulations use lower concentrations.
  • Frequency should be adjusted based on individual dryness and irritation response over time.

Conflicts & combinations

  • Avoid combining with retinoids or benzoyl peroxide in the same routine, as the combined drying and irritant effect can compromise the skin barrier.
  • Pairs reasonably with lightweight, non-comedogenic moisturizers to offset dryness.
  • Often formulated alongside other acne actives like salicylic acid, though this increases irritation risk and should be introduced cautiously and gradually.
Suitability
Suits skin type
dry oily combo sensitive acne prone mature normal
Targets
  • acne
  • enlarged pores
Use caution with
  • dryness
  • redness
Concentration
Concentration0 – 10%
Effective from
3%
Max safe
10%
Pairs well with
Frequently asked
What does sulfur do for acne?

It helps unclog pores through mild keratolytic action, reduces surface oil, and has antibacterial effects against acne-causing bacteria.

Is sulfur better than benzoyl peroxide for acne?

Sulfur is generally considered milder and less potent than benzoyl peroxide but can be a useful alternative for those who experience irritation or bleaching from benzoyl peroxide.

Why does sulfur skincare smell bad?

Sulfur compounds naturally have a sulfurous, egg-like odor; many modern formulations add fragrance or use processing methods to reduce the smell.

Is sulfur safe to use during pregnancy?

It is often cited as a pregnancy-friendly acne option, but conservative guidance still recommends checking with a healthcare provider before regular use.

Can sulfur dry out the skin?

Yes, sulfur has a drying effect, so it is best paired with a gentle, hydrating moisturizer and used at a frequency the skin tolerates.